Abstract
Objective
The aim of this study was to compare visual acuity improvement after epiretinal membrane
(ERM) surgery using air and sulfur hexafluoride (SF6) tamponade. Secondary objectives were to evaluate Visual Function Questionnaire (VFQ)
scores and central retinal thickness (CRT) changes.
Design
This was a prospective, randomized study.
Participants
Thirty-two patients were prospectively randomized, 19 to the air group and 13 to the
SF6 group.
Methods
This study has enrolled patients with ERM from clinical practice of 4 vitreoretinal
surgeons. Preoperative and postoperative data included best-corrected visual acuity
(BCVA) with the use of the Early Treatment Diabetic Retinopathy Study (ETDRS) chart,
VFQ scores, CRT, and cataract staging. Pars plana vitrectomy with ERM peeling was
performed on all patients, either with partial air tamponade or with complete SF6 tamponade.
Results
Mean BCVA improved by 0.07 logMAR (3.5 ETDRS letters) in the air group and by 0.09
logMAR (4.5 ETDRS letters) in the SF6 group (p = 0.58). There was no statistically significant difference between the groups with
regard to BCVA, VFQ scores, and CRT. The groups had similar rates of cataract progression
and adverse events.
Conclusions
ERM peeling with partial air tamponade or with complete SF6 tamponade have similar outcomes in terms of BCVA, VFQ scores, CRT, cataract development,
and adverse events.
Résumé
Objet
Comparer l’efficacité d’une tamponnade d’air et de SF6 sur l’amélioration de l’acuité visuelle chez les patients opérés pour membrane épirétinienne
(MER). Les objectifs secondaires sont d’évaluer la différence de résultat sur le score
de qualité de vie (VFQ) et sur l’épaisseur centrale de la rétine (ECR).
Nature
Étude randomisée contrôlée, prospective.
Participants
32 patients ont été randomisés de manière prospective entre les groupes Air (n=19)
et SF6 (n=13).
Méthodes
Cette étude a recruté des patients avec une MER dans la pratique clinique de 4 chirurgiens
rétinologues. Les données pré- et post-opératoires recueillies étaient la meilleure
acuité visuelle corrigée (MAVC) sur la charte Early Treatment Diabetic Retinopathy
Study (ETDRS), le score VFQ, l’ECR et le degré de cataracte. Tous les participants
ont eu une vitrectomie par la pars plana et pelage de MER, soit avec une tamponnade
partielle d’air ou une tamponnade complète de SF6.
Résultats
La MAVC s’est améliorée de 0.07 logMAR (3.5 lettres ETDRS) dans le groupe Air et de
0.09 logMAR (4.5 lettres ETDRS) pour le groupe SF6 (p=0.58). Il n’y avait pas de différence statistiquement significative entre les
deux groupes pour la MAVC, le VFQ ou l’ECR. Le taux de développement de cataracte
et de complications est semblable pour les deux groupes.
Conclusion
La tamponnade partielle d’air et la tamponnade complète de SF6 dans le pelage de MER atteignent des résultats similaires au niveau de la MAVC, du
score de VFQ, de l’ECR, du développement de cataracte et de complication.
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References
- Idiopathic epiretinal membrane and vitreomacular traction preferred practice pattern guidelines.Ophthalmology. 2016; 123: P152-P181
- The epidemiology of epiretinal membranes.Trans Am Ophthalmol Soc. 1994; 92 (discussion 425–30): 403-425
- Pathological changes in the vitreoretinal junction 1: epiretinal membrane formation.Eye (Lond). 2008; 22: 1310-1317
- Prevalence and associations of epiretinal membranes. The Blue Mountains Eye Study, Australia.Ophthalmology. 1997; 104: 1033-1040
- Idiopathic epiretinal membrane.Retina. 2014; 34: 2317-2335
- Macular epiretinal membranes.in: Ryan S.J. Schachat A.P. Charles P.W. The Retina. 4th ed. Elsevier, St Louis, MO2006
- Removal of epimacular membranes.Ophthalmology. 1985; 92: 1975
- Vitrectomy for macular pucker after treatment of retinal tears or retinal detachment.Arch Ophthalmol. 1988; 106: 758-760
- Removal of epimacular membranes.Ophthalmology. 1985; 92: 1075-1083
- Prognostic factors in surgical treatment of epiretinal membranes.Klin Monatsbl Augenheilkd. 1994; 204: 309-312
- Intra-ocular gas.in: Ryan S.J. Schachat A.P. Charles P.W. The Retina. Elsevier, St. Louis, MO2006
- Morphologic and functional outcome of epiretinal membrane surgery with and without gas tamponade—a pilot study.IOVS. 2014; 55: 3829
- Development of the 25-item National Eye Institute Visual Function Questionnaire (VFQ-25).Arch Ophthalmol. 2001; 119: 1050-1058
- The Lens Opacities Systems III. The Longitudinal Study of Cataract Study Group.Arch Ophthalmol. 1993; 111: 831-836
- Comparative study of 23-gauge vitrectomy versus 20-gauge vitrectomy for the treatment of rhegmatogenous retinal detachment.Arch Clin Exp Ophthalmol. 2011; 249: 1459-1468
- Visual outcomes with 23-gauge transconjunctival sutureless vitrectomy.Retina. 2008; 28: 258-262
- Small-gauge vitrectomy does not protect against nuclear sclerotic cataract.Retina. 2012; 32: 499-505
- Prospective randomized trial: outcomes of SF6 versus C3F8 in macular hole surgery.Can J Ophthalmol. 2015; 50: 95-100
Feng H, Adelman R. Cataract formation following vitreoretinal procedures. Clin Ophthalmol. 2104;8:1957–1965.
- Basic and Clinical Science Course, Section 12: Retina and Vitreous.AAO, Washington DC20162017: 346
Article info
Publication history
Published online: December 23, 2016
Accepted:
November 1,
2016
Received:
March 18,
2016
Identification
Copyright
© 2016 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.