In 1856, Virchow first described myelinated retinal nerve fibres (MNFs) as “chalk-white spots” around the optic disk.
1The prevalence of MNFs is about 1% based on the autopsy study.
- Virchow V.R.
Zur pathologischen anatomic der netzaut und des scherven.
Virchows Arch Pathol Anat. 1856; 10: 170-193
2The relationship among MNFs, myopia, and amblyopia is complex, and the visual prognosis is variable.
- Straatsma B.R.
- Foos B.Y.
- Heckenlively J.R.
- Taylor G.N.
Myelinated retinal nerve fibers.
Am J Ophthalmol. 1981; 91: 25-38
- Tarabishy A.B.
- Alexandrou T.J.
- Traboulsi E.I.
Syndrome of myelinated retinal nerve fibers, myopia, and amblyopia: A review.
Surv Ophthalmol. 2007; 52: 588-596
We describe the case of a 6-year-old boy who presented with blurry vision of the right eye over 2 months. On examination, his visual acuity was 20/300 OD and 20/20 OS. Pupils did not show a relative afferent papillary defect. The cycloplegic refraction OD was −6.50 +0.25 ×180 and +0.50 sphere OS. His anterior segment examination was unremarkable. Fundus OD displayed prominent MNFs (Fig. 1A). His findings are consistent with the syndrome of MNFs, myopia, and amblyopia.
- Zur pathologischen anatomic der netzaut und des scherven.Virchows Arch Pathol Anat. 1856; 10: 170-193
- Myelinated retinal nerve fibers.Am J Ophthalmol. 1981; 91: 25-38
- Syndrome of myelinated retinal nerve fibers, myopia, and amblyopia: A review.Surv Ophthalmol. 2007; 52: 588-596
Published online: April 18, 2017
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