Massive orbital teratoma

Published:August 24, 2020DOI:
      This 41-year-old woman had a left eye mass that slowly enlarged from a grain-sized lesion of the eyelid at birth to the present fist-sized mass in the orbit (Fig. 1A). The left eye was blind since birth. She had no prior ophthalmic treatment. On examination the left eye had no light perception, and no recognizable globe structure was seen in the interpalpebral area or on magnetic resonance imaging (Fig. 1B). At surgery, exenteration was performed for the 8 cm × 6 cm lesion, which weighed 300 g (Fig. 1C). Choroid-like tissue, squamous epithelium, ciliated columnar epithelium, adipose tissue, striated muscle tissue, keratinous compounds, as well as many infiltrated multinucleated giant cells were observed in the tumour specimen (Fig. 1D), which was consistent with the diagnosis of teratoma.
      Fig 1
      Fig. 1(A) Left eye of the patient with a fist-sized mass protruding in the orbital region. (B) Magnetic resonance imaging showed no recognizable globe structure in the left orbital region. (C) Gross view of neoplasm (upper-left image indicates that the neoplasm presents cystic solid in section). (D1) Combined pathological image from 2 adjacent photographs (hematoxylin-eosin staining, 40 ×) shows the ectoderm-epidermal appendages. (D2) Black arrow indicates bone tissue from mesoderm (hematoxylin-eosin staining, 100 ×). (D3) Black arrow indicates pseudostratified ciliated columnar epithelium from endoderm (hematoxylin-eosin staining,100 ×).
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