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Intracrystalline Ozurdex® implant: iatrogenic intravitreal injection management

Published:October 04, 2021DOI:https://doi.org/10.1016/j.jcjo.2021.08.009
      The intravitreal dexamethasone implant Ozurdex® (Allergan, Inc, Irvine, Calif.) is indicated for the treatment of diabetic macular edema, venous occlusion of the retinal vessels, and noninfectious uveitis. In phakic patients, it is suggested that the injection should be done 4 mm posterior to the corneal limbus, directing the needle to the optic nerve, preferably in the inferotemporal quadrant. Although it is a rare event, inadvertent intracrystalline injection of the dexamethasone implant has been reported in the literature and can lead to complications such as cataract, glaucoma, and visual impairment.
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