Abstract
Objective
To review the clinical usefulness of chorioretinal biopsies in diagnostically undefined
cases of intraocular inflammation or chorioretinal lesions.
Design
Retrospective case series.
Participants
Seven patients who underwent chorioretinal biopsies.
Methods
This case series included all consecutive patients who underwent chorioretinal biopsies
in 2 academic tertiary care centres in the province of Quebec between 2014 and 2020.
Results
A total of 7 patients were included in the study. Five patients with intraocular inflammation
underwent chorioretinal biopsies to rule out an infectious or neoplastic etiology,
whereas 2 patients underwent biopsies for suspicion of neoplastic chorioretinal masses.
Final diagnoses included primary chorioretinal lymphoma (n = 2), toxoplasmosis (n = 1),
benign choroidal mass (n = 1), nonnecrotizing granuloma (n = 1), and peripheral exudative
hemorrhagic chorioretinopathy (n = 1). No specific diagnosis was defined in 1 case
of panuveitis with scleritis. No postoperative complications were reported.
Conclusions
Chorioretinal biopsies clarified the diagnosis in 6 of 7 patients, including a definitive
diagnosis of lymphoma in 2 patients. This is a high rate of diagnosis that also represents
clinically meaningful results that influence management. Future directions include
identifying patients in whom adjuvant chorioretinal biopsy would yield a high rate
of diagnosis.
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Article Info
Publication History
Published online: June 15, 2022
Accepted:
May 23,
2022
Received in revised form:
April 10,
2022
Received:
January 25,
2022
Publication stage
In Press Corrected ProofIdentification
Copyright
© 2022 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.
