T-cell acute lymphocytic leukemia with bilateral optic nerve head infiltrates

Published:September 23, 2022DOI:
      A 9-year-old male diagnosed with T-cell acute lymphocytic leukemia and defaulted chemotherapy presented with progressive visual decline OU. The patient denied perception of light OD and had a visual acuity of 20/200 OS. Fundus examination revealed massive optic nerve head infiltration of leukemic cells OU with combined occlusion of the central artery and vein with inferior exudative retinal detachment OD (Fig. 1A) and peripapillary circinate subretinal fluid accumulation OS (Fig. 1B). An emergency hemato-oncology review was done, and chemotherapy was reinitiated. The patient, however, passed away at 1 month of follow-up from systemic metastasis.
      Fig 1
      Fig. 1Fundus photographs depicting bilateral leukemic optic nerve head infiltrates with combined vascular occlusion and inferior exudative detachment OD (figure 1A) and peripapillary circinate subretinal fluid OS (figure 1B).
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Canadian Journal of Ophthalmology
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect