An 82-year-old female patient was referred for surgical repair of a full-thickness retinal macular hole associated with profound vision loss in the right eye. She was otherwise healthy and had no history or family history of muscle weakness. Slit-lamp examination revealed needle-like polychromatic crystals within the deep cortex of the crystalline lens (Fig. 1A). With retroillumination, in which the angle of light is perpendicular to the cataract, only an outline of the crystals is seen (Fig. 1B).