- Congenital corneal opacities (CCO) are rare, with an incidence of 1 in 26,000 to 37,000 live births.1,2 There is a wide spectrum of CCO disease severity from mild and small opacities to fully opaque cornea with severe lens involvement and vascularization or conjunctivalization of the cornea. The severe form of CCO is usually associated with large corneal opacity and the presence of extensive superficial corneal vascularization. Such eyes may have conjunctival epithelial ingrowth, which can increase the risk of allograft rejection.
- Congenital iris lesions are rare and generally identified early in life.1,2 A pigmentary lesion on the iris ranges from a simple nevus or cyst to tumors including melanoma. These lesions can arise from both iris stroma and iris epithelium.2 Thorough examination as well as anterior segment imaging studies may be required to establish a diagnosis.3 Here, we report a rare case of congenital iris stromal defect masquerading as an iris tumour.
- Rosai-Dorfman disease is a rare systemic histioproliferative disease characterized clinically by cervical lymphadenopathy and pathologically by lymph node sinuses containing histiocytes with intact phagocytosed lymphocytes (emperipolesis).1