- Adult orbital xanthogranulomatous disease is a rare non-Langerhans cell histiocytic condition with 4 clinical subtypes: adult‐onset xanthogranuloma, adult‐onset asthma with periocular xanthogranuloma, necrobiotic xanthogranuloma (NBX), and Erdheim–Chester disease (ECD). We report, to our knowledge, the first case of ECD with limbal infiltration.
- Necrotizing fasciitis (NF) of the periorbital region is a rare occurrence, though has been shown to cause severe facial disfigurement, blindness, and death.1,2 We report a case of community-acquired methicillin-resistant Staphylococcus aureus (MRSA)–associated periorbital NF in a 25-year-old woman, who presented with left eye and nostril redness and swelling after picking a pimple on her nose a few days prior. She had no significant medical history and was not diabetic. She was initially diagnosed with facial cellulitis and commenced on antibiotics, but returned 2 days later with worsening cellulitis, bilateral leg pain and redness, and shortness of breath.
- Granulomatosis with polyangiitis (GPA) is a multisystemic, antineutrophil cytoplasmic antibody (ANCA)–associated small vessel vasculitis. The orbit and ocular tissues are implicated in approximately a third of cases.1 Common manifestations are conjunctivitis, episcleritis, orbital inflammation, and uveitis.1
- We report a case of subperiosteal orbital hemorrhage secondary to sinusitis resulting in visual loss. A 74-year-old male presented to a rural emergency department with a less than 12-hour history of right-sided peri-orbital swelling and subsequent loss of vision in the eye. He had been generally unwell for 2 days before presentation with neck pain and frontal headache. Medical history included Parkinson's disease and his medications included Aspirin.
- Amyloidosis is a heterogeneous collection of conditions that presents with variable organ dysfunction due to extracellular aggregation of abnormally folded proteins. Systemic light chain amyloidosis is an uncommon disease, and involvement of orbital structures is particularly rare. We present a case of chronic dacryoadenitis in which λ light chain amyloid deposition was detected in the lacrimal gland 6 months after a nonspecific biopsy.
- Sino-orbital aspergillosis is an uncommon condition that occurs when infection of the paranasal sinuses extends into the orbit. Infection most frequently originates from the maxillary sinus, followed by the ethmoid and sphenoid sinuses. The frontal sinus is rarely involved, and is largely infected secondary to adjacent sinuses. Isolated aspergillosis of the frontal sinus is extremely uncommon, with approximately 30 cases reported in the literature.1–3 Here, we present a case of invasive sino-orbital aspergillosis arising from isolated frontal sinus infection in an immunocompromised patient.
- Sebaceous adenomas (SA) are rare tumours that have commonly been regarded as pathognomonic of the rare autosomal dominant cancer predisposition syndrome, Muir–Torre syndrome.1 We present 2 cases of isolated eyelid SA and examine their clinical features and investigations for association with Muir–Torre syndrome.
- Pyoderma gangrenosum (PG) is a rare inflammatory skin condition of unknown etiology. In rare cases, it affects the eyelid, where it can have devastating visual consequences. We describe a case of severe eyelid PG, successfully managed with aggressive chronic immunosuppression.