Amyloidosis is a heterogeneous group of rare disorders wherein insoluble fibrillar proteins are deposited in extracellular spaces within the body. The disorders may be localized, systemic, hereditary, and nonhereditary. Various subtypes of amyloid proteins are involved, and are most accurately characterized by mass spectrometry. We report herein a unique case of unsuspected bilateral localized intratarsal amyloid within specimens derived from blepharoptosis surgery. Bilateral focal dystrophic calcification and bone formation were present within the amyloid deposits, a unique finding in the eyelids.
Amyloidosis is a heterogeneous group of rare disorders wherein insoluble fibrillar proteins are deposited in extracellular spaces within the body. The disorders may be localized, systemic, hereditary, and nonhereditary. Various subtypes of amyloid proteins are involved, and are most accurately characterized by mass spectrometry. We report herein a unique case of unsuspected bilateral localized intratarsal amyloid within specimens derived from blepharoptosis surgery. Bilateral focal dystrophic calcification and bone formation were present within the amyloid deposits, a unique finding in the eyelids.