- Acute retinal necrosis (ARN) is a potentially blinding condition characterized by rapidly progressive peripheral retinal necrosis with occlusive vasculopathy and prominent inflammatory reaction.1,2 Identification of a viral etiology can be done with polymerase chain reaction (PCR) testing of intraocular fluid, and prompt management is necessary to preserve vision. ARN caused by herpes simplex virus 2 (HSV-2) is rare, and our understanding is based on a few small case series.3 Here we present three cases of HSV-2 ARN in immunocompetent hosts with a prolonged clinical course of systemic and intravitreal antivirals.
- Syphilis is a spirochete infection transmitted through intercourse or congenital infection. Despite declining incidence since the 1990s, ocular syphilis has re-emerged in developed countries.1 We describe 5 distinct presentations of ocular syphilis to promote recognition of this increasingly prevalent disease.
- Migraine with visual aura is a common condition that affects up to 5% of the population during their lifetime.1 Visual symptoms last 5–60 minutes and may range from a fortification spectrum (zigzag figures with scintillating edges) to scotoma without positive phenomena that may resemble visual field loss.2 Here we present a case of a patient with a history of migraine who had repeated visual field loss that was erroneously diagnosed as a visual aura and suffered permanent vision loss.