- Essential thrombocythemia is a chronic myeloproliferative neoplasm that develops when megakaryocytes in the bone marrow produce an excess number of platelets.1 This chronic hematologic disorder is associated with a number of thrombotic and embolic complications, and prior cases of vision loss have been documented.1–6 We describe a rather unique case of essential thrombocythemia presenting with unilateral vision loss in a patient.
- Silver, aside from its physical properties making it popular for electric applications and in jewellery, has a history of being used to treat various medical conditions.1 It has been used to treat mental illness, epilepsy, gastrointestinal disorders, and infectious diseases and in surgical prostheses.1 A review performed by Drake and Hazelwood in 2005 suggested that metallic silver posed minimal risk to health—the most common side effects being argyria (greyish discoloration of the skin) and argyrosis (greyish discoloration of the sclera).
- Alkyl nitrite or forms of volatile nitric oxide donors have been used as recreational drugs for some time and are often referred to as “poppers.”1 Inhalation of poppers provides short periods of euphoria and myorelaxation. The general public perception is that there are no long-term sequalae to nitric oxide abuse.2 Additionally, poppers are frequently used to facilitate anal intercourse due to their pharmacological actions at the anal sphincter. The sale of poppers for recreational purposes was banned in Canada in 2013 because of the serious health risks they pose, especially when combined with other drugs or prescription medication.