Although rare in the nontransplant setting, several forms of corneal endotheliitis have been described.1 Viral replication (HSV, VZV, CMZ, and mumps) within the endothelium is a proposed etiology although response to antivirals and topical corticosteroids has been variable.2–8 Multiple parallel-line endotheliitis (MPLE) is a rare form of endothelial inflammation characterized by horizontal lines of endothelial dots, stromal edema, and minimal anterior chamber reaction.9–11 We present a case of MPLE and discuss the current literature on this emerging clinical entity.
Although rare in the nontransplant setting, several forms of corneal endotheliitis have been described.1 Viral replication (HSV, VZV, CMZ, and mumps) within the endothelium is a proposed etiology although response to antivirals and topical corticosteroids has been variable.2–8 Multiple parallel-line endotheliitis (MPLE) is a rare form of endothelial inflammation characterized by horizontal lines of endothelial dots, stromal edema, and minimal anterior chamber reaction.9–11 We present a case of MPLE and discuss the current literature on this emerging clinical entity.