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Severe optic neuropathy as the presenting sign of leptomeningeal carcinomatosis from pancreatic cancer
Canadian Journal of OphthalmologyVol. 55Issue 6e207–e209Published online: June 7, 2020- Armin Farahvash
- Jennifer J. Knox
- Jonathan A. Micieli
Cited in Scopus: 2Pancreatic cancer is one of the deadliest cancers in North America with an overall 5-year survival rate of less than 10%.1 The majority of pancreatic solid tumours metastasize to other organs, mainly to the liver and other peritoneal organs.1 Leptomeningeal metastasis (LM) or carcinomatous meningitis is infiltration of cancer cells to the leptomeninges and cerebrospinal fluid and is extremely rare in the setting of pancreatic adenocarcinoma with only 19 English cases reported (Supplementary Table 1, available online).