Inadvertent corneal stromal staining by trypan blue following Descemet's membrane endothelial keratoplastyTrypan blue is an azo dye solution that effectively stains basement membranes such as the anterior lens capsule and Descemet's membrane.1 In Descemet's membrane endothelial keratoplasty (DMEK), where the host Descemet's membrane and corneal endothelium are initially removed, trypan blue is used to stain the donor graft before injection to provide visibility during the unscrolling process in the anterior chamber. Trypan blue can also be injected after the descemetorrhexis and before graft injection to visualize any irregular tags or retained Descemet's membrane, both of which may increase the risk for graft detachment.
Pagetoid spread of sebaceous cell carcinoma to the corneaSebaceous cell carcinoma (SebCC) is a malignancy that most commonly presents in the eyelid.1 Pagetoid spread to the conjunctiva has been well documented,1-3 but spread to the cornea is less common.4 We report a 64-year-old female who was diagnosed with pagetoid spread of SebCC to her right cornea. She initially presented with a 3-year history of red eyes and trichiasis. After multiple epilations, she was referred to the oculoplastics service for electrolysis. On examination, her visual acuity was 20/70 in the right eye and counting fingers in the left eye (the vision was limited due to a central stromal scar and a dense cataract).