Giant cell arteritis (GCA) is a potentially fatal medium- to large-vessel vasculitis with ocular and systemic involvement. The most common ocular manifestation is anterior arteritic ischemic optic neuropathy (AAION), which can be blinding and may affect 1 or both eyes. Systemically, aortitis is the most serious potential complication of GCA, as it can lead to aortic dissection and aortic aneurysms.1