- Bonafide cysts of the lacrimal sac are rare, with only a few reports in the literature.1–3 Most are probably congenital in origin while others may be acquired. The epithelial lining of these cysts can be squamous or ciliated-respiratory in type, depending on the region of the sac lining that spawns the lesion. Conjunctival cysts arising from the medial regions of the forniceal conjunctiva must be distinguished from cysts deriving from the lacrimal sac. Other cyst-like conditions may be formed by closure of a dacryocystocele as a result of trauma or inflammation.
- Ocular surface squamous neoplasia (OSSN) is a term that incorporates dysplastic lesions originating within the epithelium of the conjunctiva or cornea, including conjunctival intraepithelial neoplasia (CIN) and invasive squamous cell carcinoma. When occurring at the limbus—the most common location—a gelatinous, papillary, or leukoplakic appearance is displayed.1 Corneal extension usually displays a thin, translucent, grey “frosted” zone. We describe herein an unusual case of limbal conjunctival squamous cell carcinoma that extended as a substantial mass onto the cornea and contained multiple clinically-apparent microcysts.
- Amyloidosis is a heterogeneous group of rare disorders wherein insoluble fibrillar proteins are deposited in extracellular spaces within the body. The disorders may be localized, systemic, hereditary, and nonhereditary. Various subtypes of amyloid proteins are involved, and are most accurately characterized by mass spectrometry. We report herein a unique case of unsuspected bilateral localized intratarsal amyloid within specimens derived from blepharoptosis surgery. Bilateral focal dystrophic calcification and bone formation were present within the amyloid deposits, a unique finding in the eyelids.
- Pleomorphic adenoma is a neoplasm named for its mixture of disparate tissue elements, including branching double-layered ductules within a fibroid, myxoid, cartilaginoid, and (rarely) adipocytic stroma.1 A rare cutaneous tumour presumably arising from apocrine or eccrine sweat ducts, it has been described in the eyelid, where it may occupy various locations, including the sub-brow region.1,2 Well-recognized tumours with identical histology may arise from the ductules of the major salivary glands and all portions of the lacrimal gland.
- Natural killer T-cell lymphoma (NKTL) is an uncommon form of systemic lymphoma that derives from natural killer (NK) cells or cytotoxic T lymphocytes, or both. Although nasal or paranasal sinuses are characteristically involved, occurrence within the ocular adnexa is rare where B-cell lymphomas predominate.1 We report an NKTL that was initially confined to a lower eyelid, mimicking a follicular conjunctivitis.