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- Lee, Andrew G40
- Selva, Dinesh11
- Farmer, James9
- Gupta, R Rishi8
- Kratky, Vladimir8
- Sen, Seema8
- Almeida, David RP7
- Chan, Clara C7
- Brownstein, Seymour6
- Choudhry, Netan6
- Juniat, Valerie6
- Krema, Hatem6
- Vickers, Aroucha6
- Charles, Norman C5
- Chin, Eric K5
- Gupta, Shikha5
- Kini, Ashwini5
- Aubin, Marie-Josée4
- Johnson, Davin4
- Kashyap, Seema4
- Mandelcorn, Efrem D4
- Micieli, Jonathan A4
- Hada, Maya3
- Kiratli, Hayyam3
- Mednick, Zale3
Correspondence
711 Results
- Correspondence
Kodamea ohmeri keratitis
Canadian Journal of OphthalmologyVol. 57Issue 3e106–e108Published online: October 19, 2021- Verona E. Botha
- Chris Murphy
- James McKelvie
Cited in Scopus: 0Kodamaea ohmeri is a yeast-like fungus and a rare but emerging pathogen.1 It has been identified as the causative organism in fungemia, funguria, endocarditis, cellulitis, and peritonitis, often with high fatality rates.1 To the best of our knowledge, there is only 1 previous report of K. ohmeri keratitis in the literature.2 - Correspondence
Rare case of extramacular choroidal macrovessel
Canadian Journal of OphthalmologyVol. 57Issue 3e89–e91Published online: October 19, 2021- Meira Fogel-Levin
- Alice Wong
- SriniVas R. Sadda
- K Bailey Freund
- David Sarraf
Cited in Scopus: 2Choroidal macrovessel (CM) is a rare, mostly unilateral vascular anomaly of the choroidal circulation.1 These abnormally large vessels may cause disturbances in the overlying retinal pigment epithelium (RPE) and the development of subretinal fluid. Some CMs can even masquerade as a choroidal tumour or parasitic infestation.1–3 Reports showing early filling of CMs during indocyanine green angiography (ICGA) suggest that most CMs are arterial in nature.1,3,4 The short posterior ciliary circulation is comprised of a medial and lateral posterior choroidal artery (PCA)5,6; the latter may represent the origin of most CMs and may explain why almost all previously reported CMs arise in the macula. - Correspondence
Varied management of idiopathic intracranial hypertension in female-to-male transgender patients
Canadian Journal of OphthalmologyVol. 57Issue 3e85–e87Published online: October 10, 2021- Samyuktha Melachuri
- Patricia Campos
- Peter Mortensen
- Gabrielle Bonhomme
- Susan Stefko
- Roxana Fu
Cited in Scopus: 0Idiopathic intracranial hypertension (IIH) is characterized by elevated intracranial pressure, visual disturbances, papilledema, and headache. There is an association between sex hormone excess and IIH, particularly in patients undergoing hormonal therapy for gender transition.1 The increased androgen concentration during testosterone therapy for gender reassignment presents an opportunity for studying different treatment modalities. First-line treatment of IIH involves dietary changes and a carbonic anhydrase inhibitor such as acetazolamide. - Correspondence
A masquerader epidemic: five heterogeneous ocular syphilis presentations
Canadian Journal of OphthalmologyVol. 57Issue 3e81–e83Published online: September 23, 2021- Seema Emami
- Panos G. Christakis
Cited in Scopus: 0Syphilis is a spirochete infection transmitted through intercourse or congenital infection. Despite declining incidence since the 1990s, ocular syphilis has re-emerged in developed countries.1 We describe 5 distinct presentations of ocular syphilis to promote recognition of this increasingly prevalent disease. - Correspondence
Wellness among Canadian ophthalmology resident physicians: a national survey
Canadian Journal of OphthalmologyVol. 57Issue 3e103–e106Published online: September 22, 2021- Mathew M. Palakkamanil
- Andrei-Alexandru Szigiato
- Bethany Ostrowerka
- Setareh Ziai
- Morley Kutzner
Cited in Scopus: 0Residency is a particularly stressful and dynamic period during which learners must balance the demands of patient care, education, and personal responsibilities. Evidence of high levels of burnout among resident physicians has driven the development of initiatives and programs to help address this negative consequence of residency training. As a novel topic in the realm of medical education, more information is required to further characterize the sources of burnout and depression and the nuances of various specialities. - Correspondence
Multiple myeloma with concurrent herpes zoster ophthalmicus: a case report
Canadian Journal of OphthalmologyVol. 57Issue 3e83–e85Published online: September 20, 2021- Zoya Chaudhry
- Karin Oliver
- John Galic
Cited in Scopus: 0Hyperviscosity syndrome, which typically results from elevated serum levels of monoclonal protein, can present with bleeding, retinopathy, and neurologic symptoms.1 We present a case of hyperviscosity syndrome confounded by herpes zoster reactivation in a patient with newly diagnosed multiple myeloma. - Correspondence
Delayed diagnosis of autosomal dominant optic atrophy until seventh decade of life
Canadian Journal of OphthalmologyVol. 57Issue 3e96–e100Published online: September 14, 2021- Subahari Raviskanthan
- Pranati Ahuja
- Peter W. Mortensen
- Dan Milea
- Andrew G. Lee
Cited in Scopus: 0Autosomal dominant optic atrophy (ADOA) is the most common hereditary optic neuropathy, manifesting in approximately 1 in 50 000 people, and up to 1 in 10 000 in Denmark, owing to a founder mutation.1 Isolated ADOA typically manifests in the first 2 decades of life as bilateral painless progressive vision loss and is therefore mostly diagnosed in childhood to young adulthood. We present a series of 2 older patients, aged 63 and 64 years, who had delayed ADOA diagnosis as proband patients in their families, emphasizing the point that chronological age should not be the sole determining factor for ordering testing for ADOA in cases of unexplained optic neuropathy. - Correspondence
Papilledema associated with COVID-19 multisystem inflammatory syndrome in children
Canadian Journal of OphthalmologyVol. 57Issue 3e94–e96Published online: August 24, 2021- Jennifer E. Chung
- Andrew R. Lee
- Réjean M. Guerriero
- Margaret M. Reynolds
Cited in Scopus: 1Multisystem inflammatory syndrome in children (MIS-C), also called pediatric inflammatory multisystem syndrome, is characterized by a wide range of symptoms and can present a diagnostic challenge given its myriad presentations. On top of the more well-known inflammatory manifestations of MIS-C, recent reports have also surfaced of MIS-C causing increased intracranial pressure.1,2 MIS-C can present similarly to other systemic inflammatory disorders such as Kawasaki disease and can be especially difficult to distinguish from Kawasaki disease if a Kawasaki-like presentation is accompanied by a positive test for coronavirus disease 2019 (COVID-19). - Correspondence
Late-onset bilateral epithelial ingrowth following rapid corneal decompensation owing to amantadine
Canadian Journal of OphthalmologyVol. 56Issue 4e137–e139Published online: March 18, 2021- Philippe Gros-Louis
- Stéphane Charest
- Marie Eve Légaré
Cited in Scopus: 0Epithelial ingrowth (EI) can occur at the interface between the flap and the stromal bed of the patient's cornea following laser assisted in situ keratomileusis (LASIK) surgery. The introduction of corneal epithelial cells into the interface can happen during surgery or after the procedure owing to loss of contact inhibition and the presence of a pathway to the interface. Epithelial ingrowth is a relatively uncommon complication, with a reported incidence of 3.9% following primary LASIK and up to 12.8% following enhancement with a flap lift. - Correspondence
Late progression of visual loss from ocular quinine toxicity
Canadian Journal of OphthalmologyVol. 56Issue 4e116–e119Published online: March 18, 2021- Yuanzhang Jiao
- Roderick F.J. O'Day
- Justin O'Day
- Heather G. Mack
Cited in Scopus: 0A 64-year-old Caucasian man was admitted to hospital with acute loss of vision after ingesting at least 3 grams of quinine, risperidone, and paracetamol. His medical history was significant for schizophrenia and nocturnal leg cramps. His usual medications were risperidone and quinine as required. No ophthalmic history was noted. An inpatient examination revealed bilateral no-light-perception vision and grossly constricted visual fields. Electrocardiogram showed sinus rhythm and blood tests, including glucose, haematology, liver, renal, coagulation profiles, and paracetamol levels were normal. - Correspondence
Intrastromal voriconazole for refractory infectious crystalline keratopathy associated with Candida pararugosa
Canadian Journal of OphthalmologyVol. 56Issue 4e139–e142Published online: March 18, 2021- Eleftherios I. Agorogiannis
- Stephen B. Kaye
- Esmaeil Arbabi
Cited in Scopus: 0Infectious crystalline keratopathy (ICK) is an infrequent complication of long-term topical steroid use following penetrating keratoplasty,1 classically caused by Streptococcus viridans.2 It has been reported in association with local immunosuppression after any ocular surgery (lamellar keratoplasty, cataract surgery, trabeculectomy, corneal cross-liking, and laser in situ keratomileusis), as well as in contact lens wearers, herpetic and Acanthamoeba keratitis, and corneal anaesthesia.3,4 Besides α-haemolytic streptococci,2 multiple additional microorganisms have been causally linked to ICK, including Gram-positive or -negative bacteria, atypical mycobacteria, and fungi,3 most of them bearing biofilm-forming capacity. - Correspondence
Cadaveric simulation improves ophthalmology resident confidence and preparedness for emergent ophthalmic procedures
Canadian Journal of OphthalmologyVol. 56Issue 4e133–e135Published online: March 16, 2021- Andrea A. Tooley
- Min Jun Hur
- Nirusha Lachman
- Andrew J. Barkmeier
Cited in Scopus: 1Simulation-based training programs have become an essential tool in medical education.1 Surgical simulation on platforms, including the Eyesi, which are now widely adopted throughout ophthalmology training, reduces intraoperative complication rates.2 Even virtual training utilizing computer graphics and surgical models, which may be lacking in qualities provided by real-life scenarios or cadavers, helps trainees perform faster and with fewer errors compared with trainees who went without virtual training. - Correspondence
Corneal imaging with optical coherence tomography assisting the diagnosis of mucolipidosis type IV
Canadian Journal of OphthalmologyVol. 56Issue 4e120–e121Published online: March 16, 2021- Cristina Bostan
- Grant Mitchell
- Benjamin Ellezam
- Jean-François Soucy
- Mona Harissi-Dagher
- Patrick Hamel
Cited in Scopus: 0Mucolipidosis type IV (MPS-IV, OMIM #252650), a lysosomal storage disorder caused by dysfunctional mucolipin-1, is characterized by neurologic and visual impairment, developmental delay, and achlorhydria. MCOLN1 gene mutation identification is diagnostic but requires clinical suspicion. The latter is challenging, however, because most systemic and ocular findings are nonspecific and rarely evolve simultaneously.1 Bilateral corneal clouding is the earliest hallmark sign of MPS-IV. Unlike in other metabolic causes of corneal opacification, it is owing to preferential accumulation of abnormal material in the corneal epithelium as opposed to other corneal layers. - Correspondence
Optical coherence tomography angiography in choroidal metastasis before and after treatment
Canadian Journal of OphthalmologyVol. 56Issue 4e114–e116Published online: March 11, 2021- Asadolah Movahedan
- Nathalie Massamba
- Peter Nesper
- Dimitra Skondra
Cited in Scopus: 0Choroidal metastases represent the most common intraocular malignant tumor in adults.1 With the advent of optical coherence tomography angiography (OCTA), there is a unique opportunity to visualize choroidal vascular pathologies in more detail using a noninvasive technique concurrent with anatomical evaluation of the retina, retinal pigment epithelium (RPE), and choroid. Depth-selective characterization is one of the most significant advantages of OCTA, allowing better visualization of choroid circulation and, particularly, the choriocapillaris layer, which is the main source of perfusion to the RPE and photoreceptors. - Correspondence
Late-onset recurrent Acremonium fungal keratitis after therapeutic penetrating keratoplasty
Canadian Journal of OphthalmologyVol. 56Issue 4e135–e137Published online: March 9, 2021- John Liu
- Florentina J. Freiberg
- Sonia N. Yeung
- Alfonso Iovieno
Cited in Scopus: 2Fungal keratitis is a prominent cause of blindness worldwide. Therapeutic penetrating keratoplasty (TPK) has been demonstrated as an effective treatment for fungal keratitis that does not respond to antifungal medications. Recurrent fungal infection after TPK is uncommon but occurs typically within 2 weeks after surgery.1 - Correspondence
Endoscopic cyclophotocoagulation and Kahook Dual Blade trabeculotomy in combination with phacoemulsification
Canadian Journal of OphthalmologyVol. 56Issue 4e123–e125Published online: March 2, 2021- Andrew L. Ward
- Kevin H. Chen
- Joseph W. Schmitz
Cited in Scopus: 0Convenient to perform alongside cataract surgery and relatively safe, minimally invasive glaucoma surgeries (MIGS) are growing in popularity. Few studies have examined the effect and safety of performing combined MIGS. - Correspondence
Biopsy of a diffuse anterior chamber angle melanocytoma using a Kahook Dual Blade
Canadian Journal of OphthalmologyVol. 56Issue 4e121–e122Published online: March 2, 2021- Cyril Archambault
- Guy Allaire
- Sonia Callejo
- Georges M. Durr
Cited in Scopus: 0A 68-year-old female was referred to the emergency ophthalmology clinic with a pigmented iris lesion and an intraocular pressure (IOP) of 38 in her left eye. Initial clinical assessment revealed the presence of a localized, flat, plaque-like peripheral and midperipheral iris lesion in one quadrant. Pigmented seeding on the rest of the iris surface and associated mild corectopia were observed. There were no notable episcleral sentinel vessels, and there was no iris neovascularization. On gonioscopy, heavy pigment invaded 8 clock hours of the angle (Fig. - Correspondence
Crossed-quadrant homonymous hemianopsia in a monocular patient
Canadian Journal of OphthalmologyVol. 56Issue 4e129–e131Published online: March 2, 2021- Joseph W. Fong
- Victoria V. Ly
- Ronald A. Braswell
Cited in Scopus: 0A 75-year-old male presented to the clinic reporting that upon waking up from a nap 4 days earlier, he noticed he could “only see in certain spots.” He has an ocular history of moderate-stage primary open-angle glaucoma in both eyes, dry eye syndrome, and pseudophakia. He had previously undergone enucleation of his blind, painful right eye due to neovascular glaucoma from a previous central retinal vein occlusion. He was a former smoker, and his medical history is significant for multiple myeloma, bladder cancer, pulmonary embolism, hypertension, and hyperlipidemia. - Correspondence
Superior oblique myositis following targeted therapy for papillary thyroid carcinoma
Canadian Journal of OphthalmologyVol. 56Issue 4e125–e127Published online: February 16, 2021- Alexander M. Tseng
- Enoch T. Peng
- Shruthi H Bindiganavile
- Subahari Raviskanthan
- Nita Bhat
- Peter W. Mortensen
- and others
Cited in Scopus: 1Papillary carcinoma of the thyroid gland (PCTG) constitutes 80%–85% of thyroid cancers globally. Despite early lymphatic invasion, PCTG has a relatively indolent course and rarely metastasizes outside of the neck.1 Metastasis to the brain from PCTG is even more uncommon and usually occurs in the context of widely disseminated disease. While the mainstay of treatment for intracranial metastasis from PCTG includes surgical excision and radiotherapy, recent advances into our understanding of the molecular pathways governing PCTG have facilitated development of novel targeted chemotherapeutics. - Correspondence
Simple limbal epithelial transplantation (SLET) in conjunction with keratoplasty for severe congenital corneal opacities
Canadian Journal of OphthalmologyVol. 56Issue 3e78–e82Published online: February 5, 2021- Mahmood Showail
- Kamiar Mireskandari
- Asim Ali
Cited in Scopus: 0Congenital corneal opacities (CCO) are rare, with an incidence of 1 in 26,000 to 37,000 live births.1,2 There is a wide spectrum of CCO disease severity from mild and small opacities to fully opaque cornea with severe lens involvement and vascularization or conjunctivalization of the cornea. The severe form of CCO is usually associated with large corneal opacity and the presence of extensive superficial corneal vascularization. Such eyes may have conjunctival epithelial ingrowth, which can increase the risk of allograft rejection. - Correspondence
Junctional scotoma in moyamoya disease
Canadian Journal of OphthalmologyVol. 56Issue 4e127–e129Published online: February 1, 2021- Sean Michael Rodriguez
- Kanwal Singh Matharu
- Linda Epner
- David Dunaway
- Rod Foroozan
Cited in Scopus: 0A 66-year-old Hispanic woman presented to the eye clinic with chronic, progressively worsening vision in the right eye over 2 years associated with right-sided temporal headaches, cutaneous allodynia of the scalp, and jaw claudication. She denied fevers, chills, joint pains, nausea, photophobia, phonophobia, personal history of autoimmune disease, and family history of hereditary ophthalmological diseases. Her ocular history included pterygium removal from the OD. Seven years prior to presentation, she had an episode of light-headedness, blurry vision for 30 minutes, a severe headache, and mild weakness of the left hemiface and left body lasting 2 hours. - Correspondence
Senior-Loken syndrome secondary to IQCB1 mutation in association with retinitis pigmentosa
Canadian Journal of OphthalmologyVol. 56Issue 4e112–e114Published online: January 31, 2021- Ekta Rishi
- Sugandha Goel
- Pukhraj Rishi
Cited in Scopus: 0Senior-Loken syndrome (SLS) is a rare autosomal recessive disease characterized by nephronophthisis and early-onset retinal degeneration.1 Nephronophthisis leads to end-stage renal failure. Several genes can cause SLS, including NPHP1-6 and NPHP10.2 We herein report a case of SLS type 5 caused by IQCB1 mutation. - Correspondence
Conjunctival and periorbital petechiae presumed secondary to self-inflicted asphyxiation in a pediatric patient
Canadian Journal of OphthalmologyVol. 56Issue 3e96–e98Published online: January 30, 2021- Aaron R. Kaufman
- Daniel J. Oh
- Ariel Gliksberg
- Mary Lou Schmidt
- Mehmet C. Mocan
Cited in Scopus: 0The presence of petechiae of the face and conjunctiva is a well-described finding seen in strangulation injuries. These petechiae are commonly seen post-mortem in deaths by asphyxia and are consequently used in forensic analysis.1 Conjunctival and facial petechiae have also been noted to occur in nonfatal asphyxia, and their presence may be a sign that a severe strangulation injury has occurred.2 The mechanism for facial and conjunctival petechial hemorrhages in asphyxia is thought to be rupture of capillaries with little connective tissue support secondary to local pressure elevation from continued arterial flow while venous output is obstructed. - Correspondence
Murine typhus presenting as pseudotumor cerebri
Canadian Journal of OphthalmologyVol. 56Issue 4e131–e133Published online: January 30, 2021- Sugi Panneerselvam
- Nita Bhat
- Shruthi Harish Bindiganavile
- Andrew G. Lee
Cited in Scopus: 0Murine typhus is an acute infection transmitted by rodent or cat fleas carrying gram-negative, obligate intracellular bacteria, Rickettsia typhi. This vector for transmission is most often carried on rodents, but opossums are thought to be a reservoir in suburban settings.1 Associated with overcrowding, pollution, and poor hygiene, murine typhus has been documented worldwide, but the majority of cases in the United States are in Texas and California.2 - Correspondence
Central retinal artery occlusion associated with Sweet syndrome
Canadian Journal of OphthalmologyVol. 56Issue 3e103–e105Published online: January 22, 2021- Helya Aghazadeh
- David Sia
- David Ehmann
Cited in Scopus: 1A 64-year-old Caucasian man presented with a 1-day history of acute painless vision loss in the right eye. On examination, his visual acuity was hand motions OD and 20/30 OS. His intraocular pressures were normal OU and he had a 3+ relative afferent pupillary defect OD. The anterior segment examination was unremarkable OU. Fundoscopic examination of the right eye revealed a cherry red spot (Fig. 1A). No vitreous cell, vasculitis, or chorioretinitis was noted OU. A fluorescein angiogram of the right eye showed an arterial filing line (Fig.