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Canadian Journal of Ophthalmology
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  • Research Letter

    Accuracy of self-reported risk factors for hydroxychloroquine retinopathy

    Canadian Journal of Ophthalmology
    Vol. 57Issue 1p65–66Published online: February 16, 2021
    • Christopher M. Santilli
    • Amy Garbo Maxey
    • Christine A. Lattery
    • Emmett F. Carpel
    • Karen R. Armbrust
    Cited in Scopus: 0
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      Hydroxychloroquine (HCQ) is an effective and typically well-tolerated anti-inflammatory medication, but retinal toxicity is a potential side effect.1 Current screening guidelines recommend baseline ophthalmic examination to rule out maculopathy and then yearly examination with visual field and optical coherence tomography after 5 years of HCQ use.1 The presence of HCQ retinopathy risk factors,2 such as HCQ duration ≥5 years, HCQ daily dose >5 mg/kg real body weight, tamoxifen use, or renal disease, should increase suspicion for retinopathy and may modify the retinopathy screening timeline.
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