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Management of patients with ocular neuropathic pain
Canadian Journal of OphthalmologyVol. 55Issue 4p342Published online: March 20, 2020- Jaime C. Sklar
- Vishakha Thakrar
- Raymond Stein
- Barbara Caffery
- Jennifer Liao
- Clara C. Chan
Cited in Scopus: 0The cornea, although relatively small, measuring 11.5 mm in diameter and 0.5–0.8 mm in thickness, is one of the most densely innervated structures of the human body.1 The nerves of the cornea are susceptible to damage by noxious stimuli, resulting in perception of pain. If pain is apparent in response to benign stimuli, and/or beyond the phase of normal healing, this condition is aptly named “neuropathic pain.” Other terms used to describe this condition include “pain without stain,” “corneal neuralgia,” “keratoneuralgia,” and “corneal pain syndrome.” It has been demonstrated previously that development of keratoneuralgia can occur after iatrogenic intervention, systemic disease, and chronic dry eye.
